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Description
INCB39110 or INCB039110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis. INCB039110 produced significant improvements in sPGA, demonstrating proof of concept in chronic plaque psoriasis. 
Chemical Structure
 
Chemical Name
2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl)piperidin-4-yl)azetidin-3-yl)acetonitrile 
SMILES Code
N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1 
Theoretical Analysis
XingMo Cat#:XM101 
Product Name:Itacitinib (INCB039110) 
Synonyms:INCB39110; INCB 39110; INCB-39110; INCB039110; INCB-039110; INCB 039110; Itacitinib; 1334298-96-2 
CAS#:1334298-90-6 
Chemical Formula:C26H23F4N9O 
Exact Mass:553.1962 
Molecular Weight:553.51 
Technical Data



WARNING: This product is for research use only, not for human or veterinary use

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