+86-13524779951 sales@x-mobio.com
Products
  APIs
  Anti-tumor series
  Antithrombotic series
  Anti-HCV series
  Rheumatism series
  Anti-diabetic series
  Nervous system series
  Others
  Intermediates
  Featured products
  Others

This product is in stock,please ask for price.
If you have any question, please send the email to sales@x-mobio.com for the availability.We will reply to you as soon as possible.
Shipment: Products are shipped via FedEx Express.
Products
Description
Ruboxistaurin, also known as LY-333531, is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt. 
Chemical Structure
 
Chemical Name
(12E,32E,7S)-7-((dimethylamino)methyl)-22,25-dihydro-11H,21H,31H-6-oxa-1,3(3,1)-diindola-2(3,4)-pyrrolacyclononaphane-22,25-dione hydrochloride 
SMILES Code
O=C1NC(C2=C1C3=CN(C4=CC=CC=C34)CC[C@@H](CN(C)C)OCCN5C=C2C6=CC=CC=C56)=O.[H]Cl 
Theoretical Analysis
XingMo Cat#:XM443 
Product Name:Ruboxistaurin HCl 
Synonyms:Ruboxistaurin; Ruboxistaurin hydrochloride, LY-333531; LY333531; LY 333531. 
CAS#:169939-93-9 (HCl) 
Chemical Formula:C28H29ClN4O3 
Exact Mass:468.2161 
Molecular Weight:505.015 
Technical Data

Appearance: Solid powder                          

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

Tel: +8613524779951  QQ: 点击这里给我发消息
Email: sales@x-mobio.com   Web: www.x-mobio.com  沪ICP备17047952号-1
Copyright 2017 Shanghai xingMo Biotechnology Co., Ltd. All rights reserved. Supported by www.hxchem.net