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Description
AS-604850 is a selective PI3Kγ inhibitor, which significantly reduced the number of infiltrated leukocytes in the CNS and ameliorated the clinical symptoms of EAE mice. Treatment with this PI3Kγ inhibitor enhanced myelination and axon number in the spinal cord of EAE mice. PI3Kγ contributes to development of autoimmune CNS inflammation and that PI3Kγ blockade may provide a great potential for treating patients with MS. 
Chemical Structure
 
Chemical Name
(Z)-5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methylene)thiazolidine-2,4-dione 
SMILES Code
O=C(NC/1=O)SC1=C/C2=CC=C(OC(F)(F)O3)C3=C2 
Theoretical Analysis
XingMo Cat#:XM004 
Product Name:AS-604850 
Synonyms:AS604850; AS 604850; AS-604850. 
CAS#:648449-76-7 
Chemical Formula:C11H5F2NO4S 
Exact Mass:284.99073 
Molecular Weight:285.22 
Purity:>98% 
Technical Data

Appearance: Solid powder
Purity:>98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 C for short term (days to weeks), or -20 C for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

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