+86-13524779951 sales@x-mobio.com
Products
  APIs
  Anti-tumor series
  Antithrombotic series
  Anti-HCV series
  Rheumatism series
  Anti-diabetic series
  Nervous system series
  Others
  Intermediates
  Featured products
  Others

This product is in stock,please ask for price.
If you have any question, please send the email to sales@x-mobio.com for the availability.We will reply to you as soon as possible.
Shipment: Products are shipped via FedEx Express.
Products
Description
Ulixertinib, also known as BVD-523 and VRT752271, is an inhibitors of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. 
Chemical Structure
 
Chemical Name
(S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide. 
SMILES Code
O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO 
Theoretical Analysis
XingMo Cat#:XM013 
Product Name:Ulixertinib (BVD-523) 
Synonyms:BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271; Ulixertinib; 
CAS#:869886-67-9 
Chemical Formula:C21H22Cl2N4O2 
Exact Mass:432.11198 
Molecular Weight:433.33 
Purity:>98% 
Technical Data

Appearance: White to off-white solid powder

Purity:>98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). 

 



WARNING: This product is for research use only, not for human or veterinary use

Tel: +8613524779951  QQ: 点击这里给我发消息
Email: sales@x-mobio.com   Web: www.x-mobio.com  沪ICP备17047952号-1
Copyright 2017 Shanghai xingMo Biotechnology Co., Ltd. All rights reserved. Supported by www.hxchem.net