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PFI-3 is a potent and selective SMARCA2/4 bromodomain inhibitor that binds avidly to the structurally-similar SMARCA4 bromodomain and PB1(bromodomain with Kd values of 89 and 48 nM, respectively. PFI-3 is a potent, cell-permeable probe capable of displacing ectopically expressed, GFP-tagged SMARCA2-bromodomain from chromatin. 
Chemical Structure
Chemical Name
Theoretical Analysis
XingMo Cat#:XM180 
Product Name:PFI-3 
Synonyms:PFI-3; PFI 3; PFI3. 
Chemical Formula:C19H19N3O2 
Exact Mass:321.1477 
Molecular Weight:321.38 
Technical Data

Appearance: solid powder        

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). 


WARNING: This product is for research use only, not for human or veterinary use

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