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ETC-206 was identified with MNK1/2 IC50 values of 0.064/0.086 uM and an IC50 value for HeLa cell proliferation of 0.362 uM .ETC-206 also showed antitumor effects in a xenograft mouse model of BC-CML bearing K562 elF4E,and in combination with dasatinib(2.5 mg/kg) totally reduced tumor growth.A phase I trial in healthy volunteers has recently been completed. 
Chemical Structure
Chemical Name
4-(6-(4- (morpholine-4-carbonyl)phenyl)imidazo[l,2-a]pyridin-3-yl)benzonitrile 
Theoretical Analysis
XingMo Cat#:XM726 
Product Name:ETC-206 
Synonyms:ETC-206, ETC206 
Chemical Formula:C25H20N4O2 
Molecular Weight:408.459 
Technical Data

Appearance: solid powder         

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).


WARNING: This product is for research use only, not for human or veterinary use

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