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Description
A novel potent and selective, orally active URAT1 inhibitor with Ki of 57 nM, 130 and 42-fold selectivity over OAT1 and OAT3, respectively; increases the fractional excretion of urinary uric acid, and reduces plasma uric acid more effectively in vivo, compared with benzbromarone, also shows lower in vitro potential for mechanisms causing the hepatotoxicity induced by benzbromarone. 
Chemical Structure
 
Chemical Name
(3,5-dibromo-4-hydroxyphenyl)(2,3-dihydro-4H-pyrido[4,3-b][1,4]oxazin-4-yl)methanone 
Theoretical Analysis
XingMo Cat#:XM775 
Product Name:UR-1102 (Epaminurad) 
Synonyms:UR1102, Epaminurad 
CAS#:1198153-15-9 
Chemical Formula:C14H10Br2N2O3 
Exact Mass:414.053 
Molecular Weight:414.05 
Purity:>98% 
Technical Data

Appearance: solid powder         

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).

 



WARNING: This product is for research use only, not for human or veterinary use

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