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PRN2246/SAR442168is an irreversible covalent, oral small molecule with potent and durable action, designed to access the brain and spinal cord by crossing the blood-brain barrier. 
Chemical Structure
Chemical Name
4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-(prop-2- enoyl)piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5- c]pyridin-2-one 
Theoretical Analysis
XingMo Cat#:XM789 
Product Name:Tolebrutinib 
Synonyms:Tolebrutinib ,PRN-2246,SAR442168 
Chemical Formula:C26H25N5O3 
Exact Mass:455.1957 
Molecular Weight:455.518 
Technical Data

Appearance: solid powder         

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years)

Solubility: Soluble in DMSO, not in water

Shelf Life:

>2 years if stored properly.

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 ℃ for short term (days to weeks), or -20 ℃ for long term (months).


WARNING: This product is for research use only, not for human or veterinary use

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