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产品类别
  原料药
  抗癌类
  抗血栓类
  丙肝类
  风湿类
  糖尿病类
  神经系统类
  其他
  中间体
  特色产品
  其他

产品介绍
产品描述
Firategrast, also known as SB-683699 or T-0047, is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). This could decrease multiple sclerosis (MS) activity, but may compromise CNS immune surveillance. The integrins are a sort of transmembrane receptors that modulate the signal transduction from ECM to the cell. They are associated with a lot of diseases such as cancer, inflammation and thrombotic diseases. 
化学结构
 
化学名称
(2S)-2-[(2,6-difluorobenzoyl)amino]-3-[4-[4-(ethoxymethyl)-2,6-dimethoxyphenyl]phenyl]propanoic acid 
SMILES Code
O=C(O)[C@@H](NC(C1=C(F)C=CC=C1F)=O)CC2=CC=C(C3=C(OC)C=C(COCC)C=C3OC)C=C2 
基本信息
产品编号:XM704 
产品名称:Firategrast 
别名:SB-683699; SB 683699; SB683699; T-0047; T 0047; T0047; Firategrast 
CAS#:402567-16-2 
分子式:C27H27F2NO6 
精确分子量:499.1806 
分子量:499.5108 
纯度:>98% 
物化性质



该产品只供科研使用,不能给病人提供。

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